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daxxify vs botox

What’s the Difference Between Daxxify and Botox?


More About Daxxify

DaxibotulinumToxinA, a brand-new injectable therapy designed to lessen the appearance of fine lines and wrinkles, is sold under the trade name DaxxifyTM. Similar to other neuromodulators like Botox®, Dysport®, Jeuveau®, or Xeomin®, Daxxify is a completely non-surgical procedure that produces noticeable results fairly quickly but only temporarily. Glabellar lines, also called “elevens” or “frown lines,” are the vertical lines that appear between the eyebrows when the muscles in that region contract, and Daxxify has been given FDA approval to treat them. Glabellar lines appear when one squints or frowns, but with time, the wrinkles may set in permanently when one is not moving.

Results from Daxxify

Even the most severe lines and wrinkles can be significantly diminished by Daxxify. Users can anticipate a significant improvement in the treated area upon injection, giving it a smoother and younger-looking appearance.

Although Daxxify effects are impressive, they are not long-lasting. Daxxify outcomes should last for 6 to 9 months for patients. With regular “maintenance” treatments, these benefits can be kept for longer periods of time. Daxxify often provides results for twice as long as Botox and other injectables based on toxins.

How Daxxify is Used

Daxxify is an example of a “neuromodulator” that functions by relaxing the muscles that contract and result in lines and wrinkles. Daxxify momentarily blocks the nerve signals that cause muscles to contract when injected into the targeted muscles. As a result, wrinkles and frown lines around the treatment region look less prominent.

More About Botox

One of the most well-known injectable neurotoxins on the market today is Botox (Botulinum Toxin Type A). Botox is a medication made from a purified toxin produced by the Clostridium botulinum bacteria, the same toxin that can result in botulism, a potentially fatal form of food poisoning. The bacteria itself is NOT injected, and since it cannot grow in the muscles that have been treated, it cannot result in botulism. This toxin can be utilized in very small dosages for a number of medical conditions, including as wrinkle reduction, the treatment of excessive sweating (hyperhidrosis), migraines, and muscular spasms. It has also been found to lessen depression when injected into specific facial locations. The FDA has given Botox approval to treat a variety of facial wrinkles, including frown lines, crow’s feet, and forehead lines, to mention a few.

Results of Botox

When Botox became commercially available in the United States in 2002, it completely changed the wrinkle-reduction landscape. One of the earliest non-surgical alternatives, it may safely and effectively lessen the look of moderate to severe lines and wrinkles. Similar to Daxxify, Botox has transient effects that usually last 3–4 months after injection.

How Botox Is Used

Similar to Daxxify, Botox inhibits the nerve signals that lead to muscular relaxation. The appearance of the frown line or wrinkle is lessened as the muscles become “frozen” or “relaxed” as a result. Professionals in the medical field deliver Botox and similar drugs by injection. For each area of the face, one injection is typically administered during a treatment.

What are the Main Differences of Daxxify and Botox?

Both in terms of how they operate and the outcomes they produce, Daxxify and Botox are comparable. Both therapies are neuromodulators that reduce wrinkle-causing muscle contractions in the targeted areas. Even the most severe signs of aging can be effectively treated by either or both therapies. However, there are a few significant distinctions between Daxxify and Botox:

Result Length

The length of time it takes to see benefits is the key distinction between the treatments. Results from Daxxify often last 2-3 times longer than those from Botox and other neurotoxins. Contrary to Botox, which often only lasts for 3–4 months, Daxxify patients can anticipate staying wrinkle-free for 6–9 months. Daxxify’s distinct formulation—which mixes its toxin with a special protein that lengthens the toxin’s effects—is the reason it can last longer. In Botox, this protein is missing.

Patients do not need to receive as many maintenance therapy sessions since Daxxify produces results that stay longer.

Each Can Address Wrinkles

The types of wrinkles that each treatment may treat also vary significantly. The glabella (frown lines), forehead lines, and crow’s feet are among the lines and wrinkles that Botox is currently FDA approved to treat. Only glabellar lines are now FDA-approved uses for Daxxify.

Prior to Disparities

Despite belonging to the same drug class as neuromodulators, Daxxify and Botox have different formulations and are both entirely independent drugs. By obstructing nerve signals, both treatments aim to relax the muscles. However, this does not imply that the two medications’ uses or dosages can be combined. For glabellar lines, a minimum of 20 units of Botox and a minimum of 40 units of Daxxify are advised.

Time Spent on the Market

Daxxify is a very new product because the FDA only gave it its approval in 2022. Contrarily, Botox has been approved since 2002 and has been used extensively worldwide for the past 20 years to help people minimize their wrinkles. Daxxify is more recent, but the advantage of lengthier outcomes has already allowed it to overtake Botox in market share.


The price of Daxxify is often more per unit than that of Botox. This is due to the noticeably longer-lasting results that Daxxify offers. In the long run, Daxxify might be less expensive than Botox because patients only need to receive 2 treatments a year instead of 4 with Botox. In other words, Daxxify allows patients to save money by reducing the frequency of their maintenance treatments. Over time, practitioners will also use less needles, syringes, and other associated materials to treat patients, reducing waste in the environment.


The main result is that for non-surgical wrinkle removal, both Botox and Daxxify are excellent choices. Both procedures can typically reduce and even eliminate even the most severe wrinkles without surgery. They are both safe and quite effective. Although Botox can treat some wrinkles that Daxxify can’t now on label, the effects of Daxxify do stay longer. We strongly advise all readers to speak with an experienced and qualified injector about both treatment choices!



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